BDBM50584925 CHEMBL5079885

SMILES [H][C@]12Cc3ccccc3[C@]([H])([C@H](NC1=O)C(C)C)N2C(=O)c1cc(NC2CCN(CC(C)(C)F)CC2)c2nnc(C)n2n1

InChI Key InChIKey=NGXAMXNWIHBLBN-JIMJEQGWSA-N

Data  9 IC50  15 Kd

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50584925   

TargetBromodomain-containing protein 3(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584925(CHEMBL5079885)
Affinity DataKd:  200nMAssay Description:Binding affinity to human BRD3 bromodomain 2 assessed as dissociation constant by BROMOscan methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed